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GPT-6 Astra rebuilds the fruit fly connectome as a Minecraft brain

A developer used GPT-6 Astra to parse the newly released MaleCNS v1.0 fruit fly connectome and rebuild it as a working brain simulation inside Minecraft in 35 minutes.

Zentrix⌚️
@ZentrixHQArchived 2026.09.17Originally posted 2026.09.17
Zentrix⌚️ @ZentrixHQOriginally posted 2026.09.17
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Scientists spent a decade wiring a fly's brain. GPT-6 Astra recreated this in 35 minutes On September 3, HHMI Janelia, the University of Cambridge, and Google Research published MaleCNS v1.0, the first complete wiring diagram of an adult fruit fly's entire nervous system, brain, optic lobes, and ventral nerve cord together. Ten years of work. 44 person-years of manual proofreading alone. 166,700 neurons, 125 million synaptic connections, released open source under CC-BY. Two days later, a @ashebytes used GPT-6 Astra to pull that connectome apart neuron by neuron, upstream and downstream connections, cell types, circuit groups, and rebuild it as a working brain inside Minecraft. No neurochip, no GPU cluster, just NumPy and the raw connectome data. Scientists spent ten years mapping that. What Astra did was take an anatomical dataset most people can't parse and turn it into a running simulation.

This post quotes another post: x.com/ashebytes/status/2099128367756820706

x.com/zentrixhq/status/2100329745141334237Archived 2026.09.17 10:16