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GPT-6 Sol matches Nature-featured retrosynthesis model on URSA benchmark

Researchers say GPT-6 Sol matches RetroChimera, the state-of-the-art retrosynthesis planning model spotlighted in Nature four days earlier, on their URSA benchmark accepted to NeurIPS 2026.

Bogdan A. Zagribelnyy, PhD
@sumrexromanusArchived 2026.09.26Originally posted 2026.09.26
Bogdan A. Zagribelnyy, PhD @sumrexromanusOriginally posted 2026.09.26
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It is happening! GPT-6 Sol ☀️ matches the performance of the 🥇 SOTA synthesis-planning model RetroChimera, spotlighted in Nature just 4 days ago, in our URSA bench accepted for #neurips2026. The future of AI-retrosynthesis is fantastic! 1/3 🧵

x.com/sumrexromanus/status/2103535499210293374Archived 2026.09.26 09:57